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Endogenous laminin is required for human airway smooth muscle cell maturation

BACKGROUND: Airway smooth muscle (ASM) contraction underlies acute bronchospasm in asthma. ASM cells can switch between a synthetic-proliferative phenotype and a contractile phenotype. While the effects of extracellular matrix (ECM) components on modulation of ASM cells to a synthetic phenotype have...

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Main Authors: Tran, Thai, McNeill, Karol D, Gerthoffer, William T, Unruh, Helmut, Halayko, Andrew J
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1586013/
https://ncbi.nlm.nih.gov/pubmed/16968549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-7-117
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