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Multiple Novel Mutations in Plasmodium falciparum Chloroquine Resistance Transporter Gene during Implementation of Artemisinin Combination Therapy in Thailand

Mutations in the chloroquine resistance transporter gene of Plasmodium falciparum (Pfcrt) are associated with drug susceptibility status of chloroquine and other antimalarials that interfere with heme detoxification process including artemisinin. We aim to investigate whether an increase in duration...

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Publicat a:Am J Trop Med Hyg
Autors principals: Buppan, Pattakorn, Seethamchai, Sunee, Kuamsab, Napaporn, Harnyuttanakorn, Pongchai, Putaporntip, Chaturong, Jongwutiwes, Somchai
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Tropical Medicine and Hygiene 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159576/
https://ncbi.nlm.nih.gov/pubmed/30141388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.18-0401
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