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Multiple Novel Mutations in Plasmodium falciparum Chloroquine Resistance Transporter Gene during Implementation of Artemisinin Combination Therapy in Thailand

Mutations in the chloroquine resistance transporter gene of Plasmodium falciparum (Pfcrt) are associated with drug susceptibility status of chloroquine and other antimalarials that interfere with heme detoxification process including artemisinin. We aim to investigate whether an increase in duration...

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Detalhes bibliográficos
Publicado no:Am J Trop Med Hyg
Main Authors: Buppan, Pattakorn, Seethamchai, Sunee, Kuamsab, Napaporn, Harnyuttanakorn, Pongchai, Putaporntip, Chaturong, Jongwutiwes, Somchai
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159576/
https://ncbi.nlm.nih.gov/pubmed/30141388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.18-0401
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