Activation of the mismatch-specific endonuclease EndoMS/NucS by the replication clamp is required for high fidelity DNA replication

The mismatch repair (MMR) system, exemplified by the MutS/MutL proteins, is widespread in Bacteria and Eukarya. However, molecular mechanisms how numerous archaea and bacteria lacking the mutS/mutL genes maintain high replication fidelity and genome stability have remained elusive. EndoMS is a recen...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Ishino, Sonoko, Skouloubris, Stéphane, Kudo, Hanae, l’Hermitte-Stead, Caroline, Es-Sadik, Asmae, Lambry, Jean-Christophe, Ishino, Yoshizumi, Myllykallio, Hannu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
Soggetti:
Molecular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159515/
https://ncbi.nlm.nih.gov/pubmed/29846672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky460
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