Modulation of the Pyrococcus abyssi NucS Endonuclease Activity by Replication Clamp at Functional and Structural Levels

Pyrococcus abyssi NucS is the founding member of a new family of structure-specific DNA endonucleases that interact with the replication clamp proliferating cell nuclear antigen (PCNA). Using a combination of small angle x-ray scattering and surface plasmon resonance analyses, we demonstrate the for...

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Bibliographische Detailangaben
Hauptverfasser: Creze, Christophe, Ligabue, Alessio, Laurent, Sébastien, Lestini, Roxane, Laptenok, Sergey P., Khun, Joelle, Vos, Marten H., Czjzek, Mirjam, Myllykallio, Hannu, Flament, Didier
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
DNA and Chromosomes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346078/
https://ncbi.nlm.nih.gov/pubmed/22431731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.346361
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