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Management of Severe Dyslipidaemia: Role of PCSK9 Inhibitors

Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays an important role in regulation of LDL receptors on the hepatocyte surface and therefore is essential for effective removal of LDL particles from circulation. Genetic and biochemical studies have established that altered PCSK9 functionality...

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Detalhes bibliográficos
Publicado no:Eur Cardiol
Autor principal: Nicholls, Stephen J
Formato: Artigo
Idioma:Inglês
Publicado em: Radcliffe Cardiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159467/
https://ncbi.nlm.nih.gov/pubmed/30310463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15420/ecr.2018.3.2
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