PCSK9 Inhibitors for the Management of Mitotane-Induced Hypercholesterolemia in Adrenocortical Carcinoma

Background: After surgical resection in adrenocortical carcinoma (ACC), mitotane is often used as adjuvant therapy. However, mitotane can cause adverse effects, such as inducing hypercholesterolemia by stimulating HMG-CoA reductase. In addition, mitotane is a strong CYP3A4 inducer which presents a c...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Endocr Soc
Main Authors: Aurora, John A, Erenler, Feyza, Matta, Stephany, Lechan, Ronald M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Cardiovascular Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089732/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.634
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker