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Development and Validation of an HPLC-MS/MS Method for Rapid Simultaneous Determination of Cefprozil Diastereomers in Human Plasma
BACKGROUND: Both cis- and trans-cefprozil have antimicrobial activity, but their potencies are quite different. It is therefore necessary to develop a sensitive method to simultaneously determine both isomers for pharmacokinetic and bioequivalence studies. METHODS: An LC-MS/MS method, using stable i...
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| Veröffentlicht in: | Int J Anal Chem |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Hindawi
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6158942/ https://ncbi.nlm.nih.gov/pubmed/30302091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6959761 |
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