A model for the evolution of prokaryotic DNA restriction-modification systems based upon the structural malleability of Type I restriction-modification enzymes

Restriction Modification (RM) systems prevent the invasion of foreign genetic material into bacterial cells by restriction and protect the host's genetic material by methylation. They are therefore important in maintaining the integrity of the host genome. RM systems are currently classified in...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Bower, Edward K M, Cooper, Laurie P, Roberts, Gareth A, White, John H, Luyten, Yvette, Morgan, Richard D, Dryden, David T F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Nucleic Acid Enzymes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158711/
https://ncbi.nlm.nih.gov/pubmed/30165537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky760
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