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Mapping an Adeno-associated Virus 9-Specific Neutralizing Epitope To Develop Next-Generation Gene Delivery Vectors

Recent clinical trials have demonstrated the potential of adeno-associated virus (AAV)-based vectors for treating rare diseases. However, significant barriers remain for the translation of these vectors into widely available therapies. In particular, exposure to the AAV capsid can generate an immune...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Giles, April R., Govindasamy, Lakshmanan, Somanathan, Suryanarayan, Wilson, James M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158442/
https://ncbi.nlm.nih.gov/pubmed/30089698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01011-18
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