The HIV Integrase Inhibitor Raltegravir Inhibits Felid Alphaherpesvirus 1 Replication by Targeting both DNA Replication and Late Gene Expression

Alphaherpesvirus-associated ocular infections in humans caused by human alphaherpesvirus 1 (HHV-1) remain challenging to treat due to the frequency of drug application required and the potential for the selection of drug-resistant viruses. Repurposing on-the-market drugs is a viable strategy to acce...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Pennington, Matthew R., Voorhees, Ian E. H., Callaway, Heather M., Dehghanpir, Shannon D., Baines, Joel D., Parrish, Colin R., Van de Walle, Gerlinde R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158441/
https://ncbi.nlm.nih.gov/pubmed/30045987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00994-18
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