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HIV-1 Engages a Dynein-Dynactin-BICD2 Complex for Infection and Transport to the Nucleus

Human immunodeficiency virus type 1 (HIV-1) infection depends on efficient intracytoplasmic transport of the incoming viral core to the target cell nucleus. Evidence suggests that this movement is facilitated by the microtubule motor dynein, a large multiprotein complex that interacts with dynactin...

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Pubblicato in:J Virol
Autori principali: Carnes, Stephanie K., Zhou, Jing, Aiken, Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158414/
https://ncbi.nlm.nih.gov/pubmed/30068656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00358-18
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