Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

The volume of the lateral ventricles (LV) increases with age and their abnormal enlargement is a key feature of several neurological and psychiatric diseases. Although lateral ventricular volume is heritable, a comprehensive investigation of its genetic determinants is lacking. In this meta-analysis...

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מידע ביבליוגרפי
הוצא לאור ב:Nat Commun
Main Authors: Vojinovic, Dina, Adams, Hieab H., Jian, Xueqiu, Yang, Qiong, Smith, Albert Vernon, Bis, Joshua C., Teumer, Alexander, Scholz, Markus, Armstrong, Nicola J., Hofer, Edith, Saba, Yasaman, Luciano, Michelle, Bernard, Manon, Trompet, Stella, Yang, Jingyun, Gillespie, Nathan A., van der Lee, Sven J., Neumann, Alexander, Ahmad, Shahzad, Andreassen, Ole A., Ames, David, Amin, Najaf, Arfanakis, Konstantinos, Bastin, Mark E., Becker, Diane M., Beiser, Alexa S., Beyer, Frauke, Brodaty, Henry, Bryan, R. Nick, Bülow, Robin, Dale, Anders M., De Jager, Philip L., Deary, Ian J., DeCarli, Charles, Fleischman, Debra A., Gottesman, Rebecca F., van der Grond, Jeroen, Gudnason, Vilmundur, Harris, Tamara B., Homuth, Georg, Knopman, David S., Kwok, John B., Lewis, Cora E., Li, Shuo, Loeffler, Markus, Lopez, Oscar L., Maillard, Pauline, El Marroun, Hanan, Mather, Karen A., Mosley, Thomas H., Muetzel, Ryan L., Nauck, Matthias, Nyquist, Paul A., Panizzon, Matthew S., Pausova, Zdenka, Psaty, Bruce M., Rice, Ken, Rotter, Jerome I., Royle, Natalie, Satizabal, Claudia L., Schmidt, Reinhold, Schofield, Peter R., Schreiner, Pamela J., Sidney, Stephen, Stott, David J., Thalamuthu, Anbupalam, Uitterlinden, Andre G., Valdés Hernández, Maria C., Vernooij, Meike W., Wen, Wei, White, Tonya, Witte, A. Veronica, Wittfeld, Katharina, Wright, Margaret J., Yanek, Lisa R., Tiemeier, Henning, Kremen, William S., Bennett, David A., Jukema, J. Wouter, Paus, Tomas, Wardlaw, Joanna M., Schmidt, Helena, Sachdev, Perminder S., Villringer, Arno, Grabe, Hans Jörgen, Longstreth, W T, van Duijn, Cornelia M., Launer, Lenore J., Seshadri, Sudha, Ikram, M Arfan, Fornage, Myriam
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2018
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158214/
https://ncbi.nlm.nih.gov/pubmed/30258056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06234-w
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