The CCT chaperonin is a novel regulator of Ca(2+) signaling through modulation of Orai1 trafficking

Store-operated Ca(2+) entry (SOCE) encodes a range of cellular responses downstream of Ca(2+) influx through the SOCE channel Orai1. Orai1 recycles at the plasma membrane (PM), with ~40% of the total Orai1 pool residing at the PM at steady state. The mechanisms regulating Orai1 recycling remain poor...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Adv
Hauptverfasser: Hodeify, Rawad, Nandakumar, Manjula, Own, Maryam, Courjaret, Raphael J., Graumann, Johannes, Hubrack, Satanay Z., Machaca, Khaled
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2018
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157965/
https://ncbi.nlm.nih.gov/pubmed/30263962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau1935
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge