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Spatially restricted subcellular Ca(2+) signaling downstream of store-operated calcium entry encoded by a cortical tunneling mechanism

Agonist-dependent Ca(2+) mobilization results in Ca(2+) store depletion and Store-Operated Calcium Entry (SOCE), which is spatially restricted to microdomains defined by cortical ER – plasma membrane contact sites (MCS). However, some Ca(2+)-dependent effectors that localize away from SOCE microdoma...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Courjaret, Raphael, Dib, Maya, Machaca, Khaled
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060099/
https://ncbi.nlm.nih.gov/pubmed/30046136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29562-9
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