Ex Vivo Major Histocompatibility Complex I Knockdown Prolongs Rejection-free Allograft Survival

BACKGROUND: Widespread application of vascularized composite allotransplantation (VCA) is currently limited by the required lifelong systemic immunosuppression and its associated morbidity and mortality. This study evaluated the efficacy of ex vivo (after procurement but before transplantation) engi...

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Vydáno v:Plast Reconstr Surg Glob Open
Hlavní autoři: Chang, Jessica B., Rifkin, William J., Soares, Marc A., Duckworth, April, Rao, Nakul, Low, Yee Cheng, Massie, Jonathan P., Rabbani, Piul S., Saadeh, Pierre B., Ceradini, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer Health 2018
Témata:
Experimental
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157929/
https://ncbi.nlm.nih.gov/pubmed/30276052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GOX.0000000000001825
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