Ex Vivo Major Histocompatibility Complex I Knockdown Prolongs Rejection-free Allograft Survival

BACKGROUND: Widespread application of vascularized composite allotransplantation (VCA) is currently limited by the required lifelong systemic immunosuppression and its associated morbidity and mortality. This study evaluated the efficacy of ex vivo (after procurement but before transplantation) engi...

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Veröffentlicht in:Plast Reconstr Surg Glob Open
Hauptverfasser: Chang, Jessica B., Rifkin, William J., Soares, Marc A., Duckworth, April, Rao, Nakul, Low, Yee Cheng, Massie, Jonathan P., Rabbani, Piul S., Saadeh, Pierre B., Ceradini, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer Health 2018
Schlagworte:
Experimental
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157929/
https://ncbi.nlm.nih.gov/pubmed/30276052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GOX.0000000000001825
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