Ex Vivo Major Histocompatibility Complex I Knockdown Prolongs Rejection-free Allograft Survival

BACKGROUND: Widespread application of vascularized composite allotransplantation (VCA) is currently limited by the required lifelong systemic immunosuppression and its associated morbidity and mortality. This study evaluated the efficacy of ex vivo (after procurement but before transplantation) engi...

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Detalles Bibliográficos
Publicado en:Plast Reconstr Surg Glob Open
Autores principales: Chang, Jessica B., Rifkin, William J., Soares, Marc A., Duckworth, April, Rao, Nakul, Low, Yee Cheng, Massie, Jonathan P., Rabbani, Piul S., Saadeh, Pierre B., Ceradini, Daniel J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Wolters Kluwer Health 2018
Materias:
Experimental
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157929/
https://ncbi.nlm.nih.gov/pubmed/30276052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GOX.0000000000001825
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