Model‐Based Prediction of Plasma Concentration and Enterohepatic Circulation of Total Bile Acids in Humans

Bile acids released postprandially can modify the rate and extent of lipophilic compounds’ absorption. This study aimed to predict the enterohepatic circulation (EHC) of total bile acids (TBAs) in response to caloric intake from their spillover in plasma. A model for TBA EHC was combined with a prev...

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Dades bibliogràfiques
Publicat a:CPT Pharmacometrics Syst Pharmacol
Autors principals: Guiastrennec, Benjamin, Sonne, David P., Bergstrand, Martin, Vilsbøll, Tina, Knop, Filip K., Karlsson, Mats O.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157686/
https://ncbi.nlm.nih.gov/pubmed/30070437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12325
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