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Differential Splicing of ANP32A in Birds Alters Its Ability to Stimulate RNA Synthesis by Restricted Influenza Polymerase

Adaptation of viruses to their hosts can result in specialization and a restricted host range. Species specific polymorphisms in the influenza virus polymerase restrict its host range during transmission from birds to mammals. ANP32A was recently identified as a cellular co-factor affecting polymera...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Baker, Steven F., Ledwith, Mitchell P., Mehle, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157632/
https://ncbi.nlm.nih.gov/pubmed/30184493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.012
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