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Effect of Intercistronic Length on Internal Ribosome Entry Site (IRES) Efficiency in Bicistronic mRNA

Specific structures found in the mRNA of picornavirus are known to allow a cap-independent translation. These structures, named internal ribosome entry sites (IRES), are also able to favor translation of the second cistron in bicistronic mRNAs. Their mechanism of action is not well understood. In th...

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Bibliografiske detaljer
Udgivet i:Gene Expr
Main Authors: Attal, Joé, Theron, Marie-Claire, Puissant, Claudine, Houdebine, Louis Marie
Format: Artigo
Sprog:Inglês
Udgivet: Cognizant Communication Corporation 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157382/
https://ncbi.nlm.nih.gov/pubmed/10947079
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