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Absence of Internal Ribosome Entry Site-Mediated Tissue Specificity in the Translation of a Bicistronic Transgene

The 5′ noncoding regions of the genomes of picornaviruses form a complex structure that directs cap-independent initiation of translation. This structure has been termed the internal ribosome entry site (IRES). The efficiency of translation initiation was shown, in vitro, to be influenced by the bin...

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Bibliographic Details
Main Authors: Shaw-Jackson, Chloë, Michiels, Thomas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC104029/
https://ncbi.nlm.nih.gov/pubmed/10074119
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