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Absence of Internal Ribosome Entry Site-Mediated Tissue Specificity in the Translation of a Bicistronic Transgene

The 5′ noncoding regions of the genomes of picornaviruses form a complex structure that directs cap-independent initiation of translation. This structure has been termed the internal ribosome entry site (IRES). The efficiency of translation initiation was shown, in vitro, to be influenced by the bin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shaw-Jackson, Chloë, Michiels, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC104029/
https://ncbi.nlm.nih.gov/pubmed/10074119
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