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Integrative pathway-based survival prediction utilizing the interaction between gene expression and DNA methylation in breast cancer

BACKGROUND: Integrative analysis on multi-omics data has gained much attention recently. To investigate the interactive effect of gene expression and DNA methylation on cancer, we propose a directed random walk-based approach on an integrated gene-gene graph that is guided by pathway information. ME...

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Veröffentlicht in:BMC Med Genomics
Hauptverfasser: Kim, So Yeon, Kim, Tae Rim, Jeong, Hyun-Hwan, Sohn, Kyung-Ah
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157196/
https://ncbi.nlm.nih.gov/pubmed/30255812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0389-z
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