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Investigating the utility of clinical outcome-guided mutual information network in network-based Cox regression

BACKGROUND: Network-based approaches have recently gained considerable popularity in high- dimensional regression settings. For example, the Cox regression model is widely used in expression analysis to predict the survival of patients. However, as the number of genes becomes substantially larger th...

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Detalles Bibliográficos
Publicado en:BMC Syst Biol
Main Authors: Jeong, Hyun-hwan, Kim, So Yeon, Wee, Kyubum, Sohn, Kyung-Ah
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331683/
https://ncbi.nlm.nih.gov/pubmed/25708115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-9-S1-S8
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