Rare variants in the splicing regulatory elements of EXOC3L4 are associated with brain glucose metabolism in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases that causes problems related to brain function. To some extent it is understood on a molecular level how AD arises, however there are a lack of biomarkers that can be used for early diagnosis. Two popular metho...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Miller, Jason E., Shivakumar, Manu K., Lee, Younghee, Han, Seonggyun, Horgousluoglu, Emrin, Risacher, Shannon L., Saykin, Andrew J., Nho, Kwangsik, Kim, Dokyoon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156983/
https://ncbi.nlm.nih.gov/pubmed/30255815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0390-6
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