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Do changes in DNA methylation mediate or interact with SNP variation? A pharmacoepigenetic analysis

BACKGROUND: In studies with multi-omics data available, there is an opportunity to investigate interdependent mechanisms of biological causality. The GAW20 data set includes both DNA genotype and methylation measures before and after fenofibrate treatment. Using change in triglyceride (TG) levels pr...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Fisher, Virginia A., Wang, Lan, Deng, Xuan, Sarnowski, Chloé, Cupples, L. Adrienne, Liu, Ching-Ti
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156904/
https://ncbi.nlm.nih.gov/pubmed/30255765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-018-0635-6
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