Do changes in DNA methylation mediate or interact with SNP variation? A pharmacoepigenetic analysis

Abstract Background In studies with multi-omics data available, there is an opportunity to investigate interdependent mechanisms of biological causality. The GAW20 data set includes both DNA genotype and methylation measures before and after fenofibrate treatment. Using change in triglyceride (TG) l...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Virginia A. Fisher, Lan Wang, Xuan Deng, Chloé Sarnowski, L. Adrienne Cupples, Ching-Ti Liu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BMC 2018-09-01
श्रृंखला:BMC Genetics
विषय:
Causal modeling
Genomic data integration
Gene-methylation interaction
Indirect effects
Triglycerides
Genofibrate treatment
ऑनलाइन पहुंच:http://link.springer.com/article/10.1186/s12863-018-0635-6
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