Chargement en cours...
B cells with aberrant activation of Notch1 signaling promote Treg and Th2 cell–dominant T-cell responses via IL-33
The Notch-signaling pathway in a variety of mature B-cell neoplasms is often activated by gene alterations, but its role remains unclear. Here, we show that B cells harboring dysregulated activation of Notch1 signaling have an immunomodulatory effect on T cells by amplifying regulatory T (Treg) and...
Enregistré dans:
| Publié dans: | Blood Adv |
|---|---|
| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2018
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6156891/ https://ncbi.nlm.nih.gov/pubmed/30213787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018019919 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|