MiR-452 promotes an aggressive colorectal cancer phenotype by regulating a Wnt/β-catenin positive feedback loop

BACKGROUND: Aberrant activation of Wnt/β-catenin signaling pathway is considered to be an important issue in progression and metastasis of various human cancers, especially in colorectal cancer (CRC). MiR-452 could activate of Wnt/β-catenin signaling. But the mechanism remains unclear. METHODS: The...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Li, Tingting, Jian, Xiangyu, He, Han, Lai, Qiuhua, Li, Xianzheng, Deng, Danling, Liu, Tengfei, Zhu, Jiehong, Jiao, Hongli, Ye, Yaping, Wang, Shuyang, Yang, Minhui, Zheng, Lin, Zhou, Weijie, Ding, Yanqing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156870/
https://ncbi.nlm.nih.gov/pubmed/30253791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0879-z
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