HIRA directly targets the enhancers of selected cardiac transcription factors during in vitro differentiation of mouse embryonic stem cells

HIRA is a histone chaperone known to modulate gene expression through the deposition of H3.3. Conditional knockout of Hira in embryonic mouse hearts leads to cardiac septal defects. Loss of function mutation in HIRA, together with other chromatin modifiers, was found in patients with congenital hear...

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Detaylı Bibliyografya
Yayımlandı:Mol Biol Rep
Asıl Yazarlar: Saleh, Rasha Noureldin M., Dilg, Daniel, Abou Zeid, Abla A., Hashad, Doaa I., Scambler, Peter J., Chapgier, Ariane L. A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Netherlands 2018
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156767/
https://ncbi.nlm.nih.gov/pubmed/30030774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-018-4247-z
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