HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3

Chromatin remodelling is essential for cardiac development. Interestingly, the role of histone chaperones has not been investigated in this regard. HIRA is a member of the HUCA (HIRA/UBN1/CABIN1/ASF1a) complex that deposits the variant histone H3.3 on chromatin independently of replication. Lack of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dilg, Daniel, Saleh, Rasha Noureldin M., Phelps, Sarah Elizabeth Lee, Rose, Yoann, Dupays, Laurent, Murphy, Cian, Mohun, Timothy, Anderson, Robert H., Scambler, Peter J., Chapgier, Ariane L. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982693/
https://ncbi.nlm.nih.gov/pubmed/27518902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161096
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