Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate

Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells and was previously shown by us to elicit a stress response in Caenorhabditis elegans that, at lower concentrations, results in enhanced stress resistance and longer lifespan. This h...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Gille, Andrea, Turkistani, Abdullah, Tsitsipatis, Dimitrios, Hou, Xiaoqing, Tauber, Sarah, Hamann, Ingrit, Urban, Nadine, Erler, Katrin, Steinbrenner, Holger, Klotz, Lars-Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156746/
https://ncbi.nlm.nih.gov/pubmed/30261343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.09.010
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