Defective cortex glia plasma membrane structure underlies light-induced epilepsy in cpes mutants

Seizures induced by visual stimulation (photosensitive epilepsy; PSE) represent a common type of epilepsy in humans, but the molecular mechanisms and genetic drivers underlying PSE remain unknown, and no good genetic animal models have been identified as yet. Here, we show an animal model of PSE, in...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kunduri, Govind, Turner-Evans, Daniel, Konya, Yutaka, Izumi, Yoshihiro, Nagashima, Kunio, Lockett, Stephen, Holthuis, Joost, Bamba, Takeshi, Acharya, Usha, Acharya, Jairaj K.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156639/
https://ncbi.nlm.nih.gov/pubmed/30185559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808463115
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