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Defective cortex glia plasma membrane structure underlies light-induced epilepsy in cpes mutants

Seizures induced by visual stimulation (photosensitive epilepsy; PSE) represent a common type of epilepsy in humans, but the molecular mechanisms and genetic drivers underlying PSE remain unknown, and no good genetic animal models have been identified as yet. Here, we show an animal model of PSE, in...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Kunduri, Govind, Turner-Evans, Daniel, Konya, Yutaka, Izumi, Yoshihiro, Nagashima, Kunio, Lockett, Stephen, Holthuis, Joost, Bamba, Takeshi, Acharya, Usha, Acharya, Jairaj K.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156639/
https://ncbi.nlm.nih.gov/pubmed/30185559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808463115
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