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Design and development of a biorelevant simulated human lung fluid

Biorelevant fluids are required to enable meaningful in vitro experimental determinations of the biopharmaceutical properties of inhaled medicines, e.g. drug solubility, particle dissolution, cellular uptake. Our aim was to develop a biorelevant simulated lung fluid (SLF) with a well-defined composi...

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Detalhes bibliográficos
Publicado no:J Drug Deliv Sci Technol
Main Authors: Hassoun, Mireille, Royall, Paul G., Parry, Mark, Harvey, Richard D., Forbes, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156579/
https://ncbi.nlm.nih.gov/pubmed/30283501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jddst.2018.08.006
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