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Analysis of extracellular mRNA in human urine reveals splice variant biomarkers of muscular dystrophies

Urine contains extracellular RNA (exRNA) markers of urogenital cancers. However, the capacity of genetic material in urine to identify systemic diseases is unknown. Here we describe exRNA splice products in human urine as a source of biomarkers for the two most common forms of muscular dystrophies,...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Antoury, Layal, Hu, Ningyan, Balaj, Leonora, Das, Sudeshna, Georghiou, Sofia, Darras, Basil, Clark, Tim, Breakefield, Xandra O., Wheeler, Thurman M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156576/
https://ncbi.nlm.nih.gov/pubmed/30254196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06206-0
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