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Tectorigenin inhibits RANKL‐induced osteoclastogenesis via suppression of NF‐κB signalling and decreases bone loss in ovariectomized C57BL/6

Metabolism of bone is regulated by the balance between osteoblast‐mediated bone formation and osteoclast‐mediated bone resorption. Activation of osteoclasts could lead to osteoporosis. Thus, inhibiting the activity of osteoclasts becomes an available strategy for the treatment of osteoporosis. Tecto...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Ma, Chiyuan, Xu, Kai, Meng, Jiahong, Ran, Jisheng, Adel Abdo Moqbel, Safwat, Liu, An, Yan, Shigui, Wu, Lidong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156464/
https://ncbi.nlm.nih.gov/pubmed/30063119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13801
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