An Effective Way of Producing Fully Assembled Antibody in Transgenic Tobacco Plants by Linking Heavy and Light Chains via a Self-Cleaving 2A Peptide

Therapeutic monoclonal antibodies (mAbs) have evolved into an important class of effective medicine in treatment of various diseases. Since the antibody molecule consists of two identical heavy chains (HC) and two light chains (LC), each chain encoded by two different genes, their expressions at sim...

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Detalhes bibliográficos
Publicado no:Front Plant Sci
Main Authors: Lin, Yuan, Hung, Chiu-Yueh, Bhattacharya, Chayanika, Nichols, Starr, Rahimuddin, Hafsa, Kittur, Farooqahmed S., Leung, TinChung, Xie, Jiahua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Plant Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156355/
https://ncbi.nlm.nih.gov/pubmed/30283486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2018.01379
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