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Effect of Vitis vinifera hydroalcoholic extract against oxaliplatin neurotoxicity: in vitro and in vivo evidence

Oxaliplatin treatment is associated with the development of a dose-limiting painful neuropathy impairing patient’s quality of life. Since oxidative unbalance is a relevant mechanism of oxaliplatin neurotoxicity, we assessed the potential antioxidant properties of Vitis vinifera extract in reducing o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Micheli, Laura, Mattoli, Luisa, Maidecchi, Anna, Pacini, Alessandra, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156221/
https://ncbi.nlm.nih.gov/pubmed/30254294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32691-w
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