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Chlorate Specifically Targets Oxidant-Starved, Antibiotic-Tolerant Populations of Pseudomonas aeruginosa Biofilms

Nitrate respiration is a widespread mode of anaerobic energy generation used by many bacterial pathogens, and the respiratory nitrate reductase, Nar, has long been known to reduce chlorate to the toxic oxidizing agent chlorite. Here, we demonstrate the antibacterial activity of chlorate against Pseu...

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Vydáno v:mBio
Hlavní autoři: Spero, Melanie A., Newman, Dianne K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156191/
https://ncbi.nlm.nih.gov/pubmed/30254119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01400-18
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