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Fitness Landscape of Antibiotic Tolerance in Pseudomonas aeruginosa Biofilms

Bacteria in biofilms have higher antibiotic tolerance than their planktonic counterparts. A major outstanding question is the degree to which the biofilm-specific cellular state and its constituent genetic determinants contribute to this hyper-tolerant phenotype. Here, we used genome-wide functional...

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Detalles Bibliográficos
Autores principales: Amini, Sasan, Hottes, Alison K., Smith, Lincoln E., Tavazoie, Saeed
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197603/
https://ncbi.nlm.nih.gov/pubmed/22028649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002298
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