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Towards Precision Engineering of Canonical Polyketide Synthase Domains: Recent Advances and Future Prospects
Modular polyketide synthases (mPKSs) build functionalized polymeric chains, some of which have become blockbuster therapeutics. Organized into repeating clusters (modules) of independently-folding domains, these assembly-line-like megasynthases can be engineered by introducing non-native components....
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| 出版年: | Molecules |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6155766/ https://ncbi.nlm.nih.gov/pubmed/28165430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22020235 |
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