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Synthesis and Biological Evaluation of Novel 8-Morpholinoimidazo[1,2-a]pyrazine Derivatives Bearing Phenylpyridine/Phenylpyrimidine-Carboxamides

Herein we designed and synthesized three series of novel 8-morpholinoimidazo[1,2-a]pyrazine derivatives bearing phenylpyridine/phenylpyrimidine-carboxamides (compounds 12a–g, 13a–g and 14a–g). All the compounds were evaluated for their IC(50) values against three cancer cell lines (A549, PC-3 and MC...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Xu, Shan, Sun, Chengyu, Chen, Chen, Zheng, Pengwu, Zhou, Yong, Zhou, Hongying, Zhu, Wufu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155691/
https://ncbi.nlm.nih.gov/pubmed/28218676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22020310
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