ATR is a therapeutic target in synovial sarcoma

Synovial sarcoma (SS) is an aggressive soft-tissue malignancy characterised by expression of SS18-SSX fusions, where treatment options are limited. To identify therapeutically actionable genetic dependencies in SS, we performed a series of parallel, high-throughput small interfering RNA (siRNA) scre...

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Publicat a:Cancer Res
Autors principals: Jones, Samuel E., Fleuren, Emmy D.G., Frankum, Jessica, Konde, Asha, Williamson, Chris T., Krastev, Dragomir B., Pemberton, Helen N., Campbell, James, Gulati, Aditi, Elliott, Richard, Menon, Malini, Selfe, Joanna L., Brough, Rachel, Pettitt, Stephen J., Niedzwiedz, Wojciech, van der Graaf, Winette T.A., Shipley, Janet, Ashworth, Alan, Lord, Christopher J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155488/
https://ncbi.nlm.nih.gov/pubmed/29038346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-2056
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