ATR is a therapeutic target in synovial sarcoma

Synovial sarcoma (SS) is an aggressive soft-tissue malignancy characterised by expression of SS18-SSX fusions, where treatment options are limited. To identify therapeutically actionable genetic dependencies in SS, we performed a series of parallel, high-throughput small interfering RNA (siRNA) scre...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Jones, Samuel E., Fleuren, Emmy D.G., Frankum, Jessica, Konde, Asha, Williamson, Chris T., Krastev, Dragomir B., Pemberton, Helen N., Campbell, James, Gulati, Aditi, Elliott, Richard, Menon, Malini, Selfe, Joanna L., Brough, Rachel, Pettitt, Stephen J., Niedzwiedz, Wojciech, van der Graaf, Winette T.A., Shipley, Janet, Ashworth, Alan, Lord, Christopher J.
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155488/
https://ncbi.nlm.nih.gov/pubmed/29038346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-2056
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