ATR is a therapeutic target in synovial sarcoma

Synovial sarcoma (SS) is an aggressive soft-tissue malignancy characterised by expression of SS18-SSX fusions, where treatment options are limited. To identify therapeutically actionable genetic dependencies in SS, we performed a series of parallel, high-throughput small interfering RNA (siRNA) scre...

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Bibliografski detalji
Izdano u:Cancer Res
Glavni autori: Jones, Samuel E., Fleuren, Emmy D.G., Frankum, Jessica, Konde, Asha, Williamson, Chris T., Krastev, Dragomir B., Pemberton, Helen N., Campbell, James, Gulati, Aditi, Elliott, Richard, Menon, Malini, Selfe, Joanna L., Brough, Rachel, Pettitt, Stephen J., Niedzwiedz, Wojciech, van der Graaf, Winette T.A., Shipley, Janet, Ashworth, Alan, Lord, Christopher J.
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155488/
https://ncbi.nlm.nih.gov/pubmed/29038346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-2056
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