ATR is a therapeutic target in synovial sarcoma

Synovial sarcoma (SS) is an aggressive soft-tissue malignancy characterised by expression of SS18-SSX fusions, where treatment options are limited. To identify therapeutically actionable genetic dependencies in SS, we performed a series of parallel, high-throughput small interfering RNA (siRNA) scre...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Jones, Samuel E., Fleuren, Emmy D.G., Frankum, Jessica, Konde, Asha, Williamson, Chris T., Krastev, Dragomir B., Pemberton, Helen N., Campbell, James, Gulati, Aditi, Elliott, Richard, Menon, Malini, Selfe, Joanna L., Brough, Rachel, Pettitt, Stephen J., Niedzwiedz, Wojciech, van der Graaf, Winette T.A., Shipley, Janet, Ashworth, Alan, Lord, Christopher J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155488/
https://ncbi.nlm.nih.gov/pubmed/29038346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-2056
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