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Enantiomeric Aβ peptides inhibit the fluid shear stress response of PIEZO1
Traumatic brain injury (TBI) elevates Abeta (Aβ) peptides in the brain and cerebral spinal fluid. Aβ peptides are amphipathic molecules that can modulate membrane mechanics. Because the mechanosensitive cation channel PIEZO1 is gated by membrane tension and curvature, it prompted us to test the effe...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6155315/ https://ncbi.nlm.nih.gov/pubmed/30250223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32572-2 |
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