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Novel role for receptor dimerization in post-translational processing and turnover of the GRα
Glucocorticoids (GCs), acting via the glucocorticoid receptor (GRα), remain the mainstay therapeutic choice for the treatment of inflammation. However, chronic GC use, aside from generating undesirable side-effects, results in GRα down-regulation, often coupled to a decrease in GC-responsiveness, wh...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6155283/ https://ncbi.nlm.nih.gov/pubmed/30250038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32440-z |
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