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PYK2 negatively regulates the Hippo pathway in TNBC by stabilizing TAZ protein
The tumor suppressor Hippo pathway negatively regulates the transcriptional coactivators Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) to inhibit cell growth and control organ size, whereas activation of YAP and TAZ is implicated in tumorigenesis and cance...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6155151/ https://ncbi.nlm.nih.gov/pubmed/30250159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1005-z |
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