Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma

Chondrosarcomas are malignant cartilage tumors showing relative resistance to conventional chemo- and radiotherapy. Previous studies showed that chondrosarcoma cells could be sensitized to chemotherapy by inhibiting the Bcl-2 family members Bcl-2, Bcl-xl and Bcl-w using ABT-737. In this study we exp...

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Veröffentlicht in:Oncogenesis
Hauptverfasser: de Jong, Yvonne, Monderer, David, Brandinelli, Emeline, Monchanin, Morgane, van den Akker, Brendy E., van Oosterwijk, Jolieke G., Blay, Jean Yves, Dutour, Aurélie, Bovée, Judith V. M. G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155044/
https://ncbi.nlm.nih.gov/pubmed/30242253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0084-0
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