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Fast design of arbitrary length loops in proteins using InteractiveRosetta

BACKGROUND: With increasing interest in ab initio protein design, there is a desire to be able to fully explore the design space of insertions and deletions. Nature inserts and deletes residues to optimize energy and function, but allowing variable length indels in the context of an interactive prot...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Bioinformatics
Prif Awduron: Hooper, William F., Walcott, Benjamin D., Wang, Xing, Bystroff, Christopher
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154894/
https://ncbi.nlm.nih.gov/pubmed/30249181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2345-5
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